References:
- Quock, R. and Chan, J.T.: Bottled water and infant formula – proper combination and dental health. Pediatrics [Submitted]
- Chang, J.C., Hart, D.A., Estey, A.W. and Chan, J.T.: Bond strengths of CAD-CAM restorative materials on enamel with five luting cements. J Prosthet Dent. 90:18-23, 2003. Narendran, S., Chan, J.T., Turner, S.D. and Keene, H.J.: Fluoride knowledge and prescription practices among dentists. J Amer Dent Edu 70:956-964, 2006.
- Chan, J.T. and Koh, S.H.: Fluoride content in caffeinated, decaffeinated and herbal teas. Caries Research 30:88-92, 1996.
- Chan, J.T., Starck, C.M., Wild, T. and Jeske, A.H.: Influence of vitamins and iron on plasma fluoride levels in rats. Pediatric Dent. 14:37-40, 1992.
- Chan, J.T., Cheeks, L., Slagle, T. and Green, K.: Relationship between plasma and tear fluoride levels in rabbit and man. Ophthalmology Research 22:39-44, 1990.
Jarvis T. Chan, D.D.S., Ph.D.
Professor
UTHSC, Medical School, (713) 500 - 4508
Jarvis.Chan@uth.tmc.edu
Clinical use of fluoride; safety and pharmacologic considerations
Systemic fluoride obtained from drinking water or as dietary supplementation, and topical fluoride from dentifrice or professional application, have been credited with the reduction of dental caries in the US population. When patients are exposed to the recommended low dosage, side effect is limited to incipient or very mild dental fluorosis which does not pose any health concern. Our laboratory studies the pharmacokinetics of fluoride metabolism. We monitor the fluoride exposure levels of infants who are using reconstituted soy-based or diary-based infant formulae, bottled waters, and other dietary products. We study the efficacy and safety of dental products such as fluoride-releasing varnish, dental floss and glass ionomer that contain fluoride as an active ingredient. In addition, we routinely analyze the fluoride content of patients’ drinking water samples send to us by practicing dentists in the Greater Houston Metropolitan area.

